Principle Trial Trickery and the Epidemic of Fraud

Principle Trial FI
Photo Credit - © Canva Pro Content License

Oxford University’s Principle Trial Collaborative Group published their trial of Ivermectin in outpatient Covid-19 patients in the Journal of Infection on 29 February 2023. In a show of predictably compromised science, the conclusions made by the authors do not match the data provided in the body of their study. A short article by the World Council for Health and a longer piece by Dr Pierre Kory have both critiqued the publication, which we recap briefly here.

Principle Trial and the Disinformation Playbook

Ivermectin is useful for prevention and early treatment of covid-19, yet the Principle Trial allowed for participant enrolment up to 14 days after the onset of symptoms, reducing the chances for effective intervention. Early treatment is shown highly useful for those at risk of severe disease, being the elderly or those with comorbidities, yet the Principle Trial accepted all adults from the age of 18, regardless of risk factors. Combined with a much lower dose than recommended, shorter duration than indicated, and advising participants to take the treatment on an empty stomach which reduces serum concentrations of the active ingredient, this obscures any effectiveness of the treatment.

Despite these well-known tricks from the Disinformation Playbook of Big Pharma, which significantly reduced the apparent effectiveness of ivermectin, the study data showed that the ivermectin group recovered 2.06 days faster than the usual-care group, and had a 2.8% improved mortality rate. Statistically significant lower rates of ‘long covid’ symptoms were observed in the ivermectin group compared with the usual-care group. Nevertheless, the authors concluded that “Ivermectin for COVID-19 is unlikely to provide clinically meaningful improvement in recovery, hospital admissions, or longer-term outcomes. Further trials of ivermectin for SARS-Cov-2 infection in vaccinated community populations appear unwarranted.

In contrast, Dr Kory concluded that the Principle Trial is a “profoundly positive study that was instead analyzed and written up as a negative one“, due to the inconvenient outcomes to the pharmaceutical industry agenda. The World Council for Health agree with the trial authors, “that further trials of ivermectin alone are unwarranted, the weight of evidence summarised at covid19.org being so overwhelming that the remaining issues concern dosage, adjuncts, and mechanism, rather than further empirical evidence of clinical effect.

The below table from Dr Kory’s article shows the differences in trial design between a drug promising significant profits (Molnupiravir) with a drug offering no profit (Ivermectin).

Principle Trial Design Inconsistencies With Molnupiravir
Image captured for criticism/review and reporting current events under Fair Dealing – The Copyright Act 1994

Watch: Epidemic of Fraud

It is not just ivermectin which has suffered at the hands of corrupt researchers.  Hydroxychloroquine, another cheap effective early treatment, was the subject of even greater deception.

For more detail into the epidemic of fraud that we are living through, Broken Truth filmmakers have produced a recent documentary with a focus on the strategies used to dismiss hydroxychloroquine as a preventive and early treatment intervention against Covid-19, which you can watch below.

The only conclusion that can be drawn is that the pharmaceutical industry was intent on massive profits at the expense of human lives and that the regulators were in on the deal, as proclaimed by Australian Senator Malcolm Roberts here for instance. We cannot let this happen again. 

Click to rate this post!
[Total: 195 Average: 4.9]
Share this post

Similar Posts

6 Comments

  1. I’m a little confused. I read an article in mid 2023 stating that publication of the Ivermectin arm of the PRINCIPLE Trial had not occurred by that time, despite initial results coming out in August 2022. Perhaps I’ve missed something here. It’s possible the study authors had failed to release full data? Or was that The Together Trial?

  2. https://open.substack.com/pub/doyourownresearch/p/waiting-for-principle?utm_source=share&utm_medium=android&r=14q8is

    I’m a little confused. I read an article in mid 2023 stating that publication of the Ivermectin arm of the PRINCIPLE Trial had not occurred by that time, despite initial results coming out in August 2022. Perhaps I’ve missed something here. It’s possible the study authors had failed to release full data? Or was that The Together Trial?

  3. Very good work!
    Somebody should show this to former Green Party MP Nandor … because he just posted an homage to Lockdowns …
    “How The Mighty Have Fallen.”

  4. Thanks for referencing my film! I love NZ and hopefully can return to visit one day. Nice to know there are like minds there. Keep up the fight!
    John Davidson

  5. Government is usually the cause and NOT the solution to most issues. That is why I am a Libertarian and have been for years. The covid scam went only to cement that belief, and again I was vindicated when everyone around me rolled up for multiple shots, all happily professing that it was ‘safe and effective’…and as they fell one by one to multiple infections they still repeat the mantra.
    NOTHING will come out of the inquiry, I am sure of that. They will all cover their collective arses and slap each other on the back, and hide behind their selected ‘experts’. My trust in any government advice is zero, but i started at a low base anyway. The public seem unable to think from a critical base, and just go along with anything coming thru the TV as ‘fact’.

Leave a Reply

Your email address will not be published. Required fields are marked *