Brief History of Ivermectin
Ivermectin is a well known medication used to treat a range of parasitic diseases affecting billions of people in the world’s poorest communities across South America, Africa and Asia. It was initially discovered in 1973 by Japanese research scientist Satoshi Ōmura, who specialised in testing soil bacteria for potential antibiotic properties.
Ōmura provided the samples of a newly isolated bacteria Streptomyces avermectinius, to an American biologist, William Campbell, researching parasite treatments at Merck, Sharp and Dohme Research Laboratories. Campbell discovered the anti-parasitic properties of Streptomyces avermectinius which was developed into medication form and named Ivermectin by 1980. Human trials began in 1983 and approval for human use was granted in 1987. This is an example of the usual duration for sufficient safety and efficacy testing in competent drug discovery and development.
Ivermectin has since been described as a “wonder drug” for it’s broad therapeuic uses and excellent safety profile. An estimated 4 billion doses have been distributed globally, with 1 million doses distributed daily for human use. It is on the WHO Model List of Essential Medicines. Merck supply it to many poor countries at no cost as it no longer provides a large profit to the company.
In 2015 Ōmura and Campbell shared the Nobel Prize in Physiology and Medicine for their discovery of Ivermectin as a life saving therapy, with a Chinese researcher who discovered Artemisinin as a treatment against Malaria. Both therapies have had immeasurable impacts on global health, particularly in impoverished nations.
Multiple laboratory studies since 2012 have discovered Ivermectin to be useful against a variety of viruses including Influenza. Doctors treating COVID patients in early 2020 who were aware of these trials recognised the potential and began prescribing it. Clinical observations and comprehensive reviews found an association with improved disease outcomes and it was included in early treatment protocols which continue to be calibrated as clinical experience and research trials advance.
How Does Ivermectin Work?
Ivermectin remains a recommended first-line drug for pre-exposure prevention; post-exposure prevention; in the treatment of COVID disease across all phases; and in the treatment of Long-Haul COVID-19 Syndrome. It is used in multi-drug treatment regimens, which is standard for treating viral infections. Despite a high success rate there are patients who do not respond, for which alternative treatments are recommended. The protocols at Frontline Covid-19 Critical Care Alliance are an invaluable resource.
Mechanisms of action against COVID include but are not limited to:
- Inhibits viral replication;
- Inhibits viral binding to host cells;
- Potent anti-inflammatory properties;
- Profound inhibition of multiple inflammatory mediators;
- Significantly diminishes viral load to protect against organ damage;
- Prevents blood from clotting by binding to the spike protein;
- Protects the heart by increasing ATP (energy) production;
- May help to optimise the microbiome (good bugs in the gut).
Clinical trials have shown the impact of Ivermectin on COVID disease in humans as:
- Prevents transmission in those exposed to the virus;
- Prevents progression to disease in those infected with the virus;
- Hastens recovery of, and prevents deterioration in, COVID patients with mild to moderate disease when given early after symptom onset;
- Reduces ICU admissions and death in hospitalised, symptomatic COVID patients;
- Reduces mortality in patients who are critically ill with COVID;
- Striking reductions in case fatality rates in regions with widespread use.
Why the Controversy About Ivermectin?
The answer to this question appears to be pharmaceutical profits over human health and safety. As an anti-parasitic, Ivermectin is also used to treat animal infections, just as Penicillin has both animal and human treatment uses. When the FDA claimed that Ivermectin was a “horse dewormer”, they knew this was a distortion of the truth and it became apparent to many millions that they – and many of their counterparts worldwide, as well as mainstream media who promoted the story – are captured by the industry they are employed to regulate.
One of the most stunning controversies is the TOGETHER Trial in which scientific misconduct is apparent by conflicted researchers and medical publishers who deliberately misrepresent the drug as ineffective. It seems that safe, effective, established and affordable drugs such as Ivermectin and Hydroxychloroquine stand in the way of high profits to be made from unsafe, ineffective, expensive experimental therapies such as the mRNA injections and “innovative” drugs such as Paxlovid, Molnupiravir and Remdesivir.
For example, the Remdesivir trials conducted on Ebola patients in 2014 caused multiple organ failure, renal failure, septic shock and hypotension in participants who experienced a 54% mortality rate – the highest amongst four experimental drugs trialled during the outbreak. Anthony Fauci has strong financial ties with Remdesivir. It is surely negligent not to be asking what incentives are involved in drug protocol recommendations; and in every instance of COVID related death, what drugs were used and what the autopsy findings were.
In his latest Substack article, New study shows ivermectin can reduce chance of death by 92%: But the WHO, NIH, and FDA all recommend that you avoid using it, Steve Kirsch highlights the controversy. Despite clear evidence for both safety and effectiveness, World Health Organisation continue to recommend against the use of Ivermectin except in clinical trials whilst recommending new drugs with weak evidence for limited effectiveness and alarming safety profiles. Whilst Ivermectin remains absent from the New Zealand Ministry of Health recommendations, these new and expensive therapies all feature.
Dr Tess Lawrie of the World Council for Health has also written about the controversy on Substack, at Ivermectin Works – Just Not For Big Pharma, in which she introduces a fascinating new discovery which helps explain the deserving title of “wonder drug” .
Has the New Zealand Government contracted with pharmaceutical companies at the expense of the health and safety of the New Zealand people? Ivermectin has always been available in New Zealand and most doctors have prescribed it at some point in their career. Why, all around the same time in 2021, did we face a sudden supply issue, as Medsafe issued a safety alert against its use in COVID treatment, and New Zealand Customs interrupted imports?
It is hard to remain clinical and dispassionate in discussing familiar and proven life-saving early treatments like Hydroxychloroquine and Ivermectin which could have saved more than 80% of lives lost to COVID, and genuinely “protected the health system”. Doctors prescribing Ivermectin, or trying to access it to treat their high-risk patients in anticipation of the inevitable arrival of COVID faced threats and punishments. This stands in stark contrast to the shoe-in of the most untested ‘vaccine’ in history. See our previous post here for a discussion of one of the Pfizer point men in NZ.
How Can We Celebrate Ivermectin?
1. Petition the New Zealand Government to Authorise Ivermectin
New Zealand currently has one of the highest COVID death rates in the world. Ivermectin is extremely safe for human use and has been shown to be highly effective against COVID. The immediate authorisation of Ivermectin by the Ministry of Health to treat COVID will save lives.
If you agree and want to change the course of events taking place, please consider submitting your own letter to Minister of Health, Andrew Little. We have made the process easy by providing this template and submit button.
2. Hear What NZDSOS Have To Say
On Sunday 24 July at 7pm we discussed the use of Ivermectin as an effective COVID treatment at an online event supported by Voices For Freedom and The Health Forum New Zealand. Dr Naomi Dolgelmans, a GP with expertise in elderly care, and now COVID and vaccine-injured patients, joined us from The Netherlands to discuss her experiences. The New Zealand context was discussed by Pharmacist Louise Burnside and Dr Alison Goodwin (including a downloadable presentation). Retired GP Dr Janion discussed historical and recent research. A worthwhile hour of your time which you can watch at this link.
3. Share Your Support for Ivermectin
Tell people what you know, to get the word out. Have you used Ivermectin as a patient, prescriber or dispenser? Share a selfie with your Ivermectin on social media, or share your story, using the hashtags: #IvermectinWorks #WorldIvermectinDay.
4. Learn More
We recommend a visit to the World Ivermectin Day website for a wealth of interesting and useful information. This short documentary from the Frontline Critical Care Alliance tells the history of this wonder drug.